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Now showing items 63-82 of 130
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Genome variation in mycobacterium tuberculosis
(Academy of Science for South Africa, 2002)Genome variation is the main underlying reason for phenotypic differences observed between organisms from the same species. This includes minor variations like single nucleotide polymorphisms, but also large sequence ... -
Grapefruit juice improves glucose intolerance in streptozotocin-induced diabetes by suppressing hepatic gluconeogenesis.
(Springer, 2016-03)Purpose Hypoglycemic effects of grapefruit juice (GFJ) are widely recognized, but the mechanism(s) by which GFJ lowers blood glucose levels have not previously been investigated. Methods Wistar rats [250–300 g body ... -
High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection.
(2015)In chronic HIV infection, CD8+ T cell responses to Gag are associated with lower viral loads, but longitudinal studies of HLA-restricted CD8+ T cell-driven selection pressure in Gag from the time of acute infection are ... -
HIV testing behaviors and attitudes among community recruited methamphetamine users in a South African township.
(Springer, 2015-01)Methamphetamine users in South Africa are at high risk for HIV infection and transmission, but little is known about HIV testing in this population. We examined HIV testing behaviors and attitudes in 362 methamphetamine ... -
Hoarding in obsessive-compulsive disorder and related disorders: a preliminary report of 15 cases
(2002)Hoarding, the repetitive collection of excessive quantities of poorly useable items of little or no value with failure to discard these items over time, is characterized in DSM-IV as a symptom of obsessive-compulsive ... -
Home gardens focusing on the production of yellow and dark-green leafy vegetables increase the serum retinol concentrations of 2–5-y-old children in South Africa.
(American Society for Clinical Nutrition, 2002-11)Background: Production of yellow and dark-green leafy vegetables at the household level may provide economically deprived households with direct access to provitamin A-rich foods. Objective: The aim of the study was ... -
Immunohistochemical localization of zona pellucida proteins ZPA, ZPB and ZPC in human; cynomolgus monkey; and mouse ovaries
(Springer, 2001)The zona pellucida of mammalian oocytes plays an important role in binding and activation of sperm cells during the molecular events leading to fertilization. The genes coding for the three zona pellucida glycoproteins ... -
Impact after 1 year of compulsory iodisation on the iodine content of table salt at retailer level in South Africa
(Carfax., 1999)The short-term effectiveness of introducing compulsory iodisation through revised health legislation, evaluated in terms of the iodine content of iodised table salt, was investigated in three of the nine provinces in South ... -
The impact of alcohol on HIV prevention and treatment for South Africans in primary healthcare.
(2014-08)Antiretroviral treatment (ART) has substantially reduced morbidity and mortality for HIV patients. In South Africa, with the largest ART programme globally, attention is needed not only on the further expansion of ART ... -
The impact of dietary protein intake on serum biochemical and haematological profiles in vervet monkeys
(MUNKSGAARD - SUBSCRIPTION SERVICE, 2001)This study evaluated the influence of Westernised and traditional African diets on biochemical and haematological profiles in vervet monkeys (Cercopithecus aethiops). Twelve adult male vervet monkeys bred at the Medical ... -
Influence of infant-feeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa: a prospective cohort study.
(The Lancet, 1999-08-07)Background: The observation that mother-to-child transmission of HIV-1 can occur through breastfeeding has resulted in policies that recommend avoidance of breastfeeding by HIV-1-infected women in the developed world and ... -
Influence of the G2 cell cycle block abrogator pentoxifylline on the expression and subcellular location of cyclin B1 and p34(cdc2) in HeLa cervical carcinoma cells
(1999)Abstract. The progression of cells from G2 into mitosis in mainly controlled by formation of the cyclin B1/p34cdc2 complex. The behavior of this complex in the irradiation-induced G2 cell cycle delay is still unclear. A ... -
Interleukin‐6 Inhibitor, Tocolizumab, for COVID‐19: evidence review of the clinical benefit and harm
(South African National Department of Health, 2020-04-15) -
Intimate partner violence: associations with low infant birthweight in a South African birth cohort.
(2014)Violence against women is a global public health problem. Exposure to intimate partner violence (IPV) during pregnancy has been associated with a number of adverse maternal and fetal outcomes, including delivery of a low ... -
Investigating the psychosocial determinants of child health in Africa: The Drakenstein Child Health Study.
(2015-08-30)Early life psychobiological and psychosocial factors play a key role in influencing child health outcomes. Longitudinal studies may help elucidate the relevant risk and resilience profiles, and the underlying mechanisms ... -
Iron, folate and vitamin B12 status of an elderly South African population
(Basingstoke: Nature Publishing, 1997)Objectives: To determine the prevalence of anaemia and the haemopoietic nutrient status of older mixed ancestry (coloured) South Africans. Design: A cross-sectional analytic study. Subjects: A random sample of 200 ... -
Is there an association between the nutritional status of the mother and that of her 2-year-old to 5-year-old child?
(Taylor & Francis, 2005-06)The aim of this study was to determine whether there is an association between the nutritional status of the mother and that of her 2-year-old to 5-year-old child in a rural village in South Africa where there is a high ...