Loading...
A retrospective cohort study of body mass index and survival in HIV infected patients with and without TB co-infection
Naidoo, K Yende-Zuma, N Augustine, S
Naidoo, K
Yende-Zuma, N
Augustine, S
Abstract
Background
High early morbidity and mortality following antiretroviral therapy (ART) initiation has been a distinguishing feature of ART programmes in resource limited settings (RLS) compared to high-income countries. This study assessed how well body mass index (BMI: kg/m2) correlated with survival among HIV infected patients with and without TB co-infection.
Methods
We retrospectively evaluated clinical data from 1000 HIV infected patients, among whom 389 were also co-infected with TB, between January 2008 and December 2010, in KwaZulu-Natal, South Africa.
Results
Among 948 patients eligible for analysis, 15.7% (149/948) were underweight (< 18.50), 55.9% (530/948) had normal BMI (≥18.50–24.90), 18.7% (177/948) were overweight (25.00–29.00) and 9.7% (92/948) were obese (≥30.00). Irrespective of TB status, underweight patients, had significantly higher risk of death compared to those with normal BMI at baseline (aHR = 2.9; 95% CI: 1.5–5.7; P = 0.002).
Conclusions
Irrespective of TB co-infection, low BMI correlated with mortality in HIV infected patients.
Description
Date
2018-04-25
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Nature
Collections
Files
Loading...
Article
Adobe PDF, 707.29 KB
Research Projects
Organizational Units
Journal Issue
Keywords
Body mass index, HIV infected patients, TB co-infection, SDG-03 Good health and well-being
Citation
Naidoo K, Yende-Zuma N, Augustine S. A retrospective cohort study of body mass index and survival in HIV infected patients with and without TB co-infection. Infectious Diseases of Poverty. 2018;7(1):35. doi: 10.1186/s40249-018-0418-3.
License
Attribution 3.0 United States