Intra-Mural Research Outputs
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The SAMRC’s Intramural Units are the organisation’s internal research divisions which employ specialist scientists from various fields to conduct laboratory investigations, clinical research and public health studies. The Intramural Units focus their research on the leading causes of death in South Africa which include Tuberculosis (TB), HIV, Non-communicable Diseases like cardiovascular disease, and diabetes, along with alcohol and drug abuse, among others. Women’s health is another key focus area. Research conducted by the SAMRC’s Intramural Units has provided the South African government and National Department of Health with information and insights needed for health planning and assessments.
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Role of vaccines in preventing influenza in healthy children
(HMPG, 2021-03-02)The role of an influenza vaccine is to minimise illness and death. Vaccines provide good protection against influenza strains and significantly reduce time off work. However, the recommendation for use depends on the ... -
Inter-Comparison Campaign of Solar UVR Instruments under Clear Sky Conditions at Reunion Island (21◦S, 55◦E)
(MDPI, 2020-04-19)Measurement of solar ultraviolet radiation (UVR) is important for the assessment of potential beneficial and adverse impacts on the biosphere, plants, animals, and humans. Excess solar UVR exposure in humans is associated ... -
Association of deworming with reduced eosinophilia: implications of HIV/AIDS and co-endemic diseases
(2003)Eosinophil counts in venous blood were monitored during a randomized controlled deworming trial (n = 155 children) that lasted for a year, and in a whole-school deworming programme (range 174-256 children) of 2 years' ... -
Fumonisin mycotoxins in human hair
(2003)This study shows for the first time the accumulation of fumonisin mycotoxins in human hair of population clusters exposed to contaminated maize, and thus the feasibility of human hair analysis for the assessment of past ... -
Influence of the G2 cell cycle block abrogator pentoxifylline on the expression and subcellular location of cyclin B1 and p34(cdc2) in HeLa cervical carcinoma cells
(1999)Abstract. The progression of cells from G2 into mitosis in mainly controlled by formation of the cyclin B1/p34cdc2 complex. The behavior of this complex in the irradiation-induced G2 cell cycle delay is still unclear. A ... -
The MRC/Wits dental research Institute: its publication record 1954-2004.
(Academy of Science for South Africa, 2006)All 625 scientific papers published by the Dental Research Institute (DRI) during its life between 1954 and 2004 were examined and categorized according to publishing journal, article content and author, with the aim of ... -
Interleukin‐6 Inhibitor, Tocolizumab, for COVID‐19: evidence review of the clinical benefit and harm
(South African National Department of Health, 2020-04-15) -
Lopinavir–ritonavir (LPV/r) for treatment of COVID‐19: evidence review of clinical benefits and harms
(South African National Department of Health, 2020-04-22) -
Azithromycin for COVID‐19: evidence review of the clinical benefit and harm
(South African National Department of Health , 2020-05-11) -
Favipiravir for the prevention and management of COVID‐19: evidence review of the clinical benefit and harm
(South African National Department of Health, 2020-06-25) -
Corticosteroids for COVID‐19: evidence review of the ckinical benefit and harm
(South African National Department of Health, 2020-07-23) -
Remdesivir for COVID‐19: evidence review of the clinical benefit and harm
(South African National Department of Health , 2020-06-24) -
Chloroquine and hydroxychloroquine for prevention of COVID‐19: evidence review of clinical benefits and harm
(South African National Department of Health, 2020-06-18) -
Continuing Low Colon Cancer Incidence in African Populations
(Elsevier, 2000) -
Genome variation in mycobacterium tuberculosis
(Academy of Science for South Africa, 2002)Genome variation is the main underlying reason for phenotypic differences observed between organisms from the same species. This includes minor variations like single nucleotide polymorphisms, but also large sequence ... -
Melatonin prevents the free radical and MADD metabolic profiles induced by antituberculosis drugs in an animal model
(Blackwell, 2005)The objective was to determine the effect of combined antituberculosis (anti-TB) drug therapy and an antioxidant, melatonin, on the free radical and organic acid profiles in an experimental rat model. A combined anti-TB ... -
Energy management and global health
(Palo Alto, 2004)Energy and energy technologies have a central role in social and economic development at all scales, from household and community to regional and national. Among its welfare effects, energy is closely linked with public ... -
Bacille calmette‐guerin (BCG) vaccine for preventing SARS‐CoV‐2 infection or improving COVID‐19 outcome: evidence review of clinical benefits and harms.
(Wiley & Sons, 2020-05-27)Background: Convalescent plasma and hyperimmune immunoglobulin may reduce mortality in patients with respiratory virus diseases, and are currently being investigated in trials as a potential therapy for coronavirus disease ... -
The South African Community Epidemiology Network on Drug Use (SACENDU): Description, findings (1997-99) and policy implications
(Carfax, 2002)Aims: To (1) describe the South African Community Epidemiology Network on Drug Use (SACENDU), (2) describe trends and associated consequences of alcohol and other drug (AOD) use in South Africa for January 1997 to December ... -
Adolescent precursors of intensity of marijuana and other illicit drug use among adult initiators
(Washington DC Heldref, 2001)This study examined (a) adolescent psychosocial risk factors for frequency (intensity) of marijuana use and for other illicit drug use among those who started using these drugs in early adulthood (adult initiators) and (b) ...
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