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    • The use of directed evolution to create a stable and immunogenic recombinant BCG expressing a modified HIV-1 Gag antigen. 

      Chapman, Rosamund; Bourn, William R; Shephard, Enid; Stutz, Helen; Douglass, Nicola; Mgwebi, Thandi; Meyers, Ann; Chin'ombe, Nyasha; Williamson, Anna-Lise (2014-07-25)
      Numerous features make Mycobacterium bovis BCG an attractive vaccine vector for HIV. It has a good safety profile, it elicits long-lasting cellular immune responses and in addition manufacturing costs are affordable. Despite ...

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    AuthorBourn, William R (1)Chapman, Rosamund (1)Chin'ombe, Nyasha (1)Douglass, Nicola (1)Meyers, Ann (1)Mgwebi, Thandi (1)Shephard, Enid (1)Stutz, Helen (1)Williamson, Anna-Lise (1)SubjectAnimals (1)
    CD4-Positive T-Lymphocytes (1)
    CD8-Positive T-Lymphocytes (1)Cloning (1)Cytotoxic T Cells (1)Directed Molecular Evolution (1)Female (1)gag Gene Products, Human Immunodeficiency Virus (1)Green Fluorescent Proteins (1)Immune response (1)... View MoreDate Issued2014 (1)Has File(s)Yes (1)

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