Grant Funded: Journal Articles

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All papers that are published (or in the process of being published) in a scientific journal by SAMRC staff.

Recent Submissions

Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: A cluster-randomised controlled, open-label, two-by-two factorial design trial

Hsiang, M.S; Ntuku, H; Roberts, K.W; Dufuor, M.K; Whittemore, B; Munyaradzi, T; McCreesh, P; Medzhihradsky, O.F; Prach, L.M; Siloka, G; Siame, N; Smith Gueye, C; Schrubbe, L; Wu, L; Scott, V; Tessema, S; Greenhouse, B; Erlank, E; Koekemoer, L.L; Sturrock, H.J.W; Mwilima, A; Katokele, S; Uusiku, P; Bennett, A; Smith, J.L; Kleinschmidt, I; Mumbengegwi, D; Gosling, R (The Lancet, 2020-04-25)

Background: In low malaria-endemic settings, screening and treatment of individuals in close proximity to index cases, also known as reactive case detection (RACD), is practised for surveillance and response. However, other ...
Grapefruit juice improves glucose intolerance in streptozotocin-induced diabetes by suppressing hepatic gluconeogenesis.

Hayanga, J.A; Ngubane, S.P.; Murunga, A.N.; Owira, P.M (Springer, 2016-03)

Purpose Hypoglycemic effects of grapefruit juice (GFJ) are widely recognized, but the mechanism(s) by which GFJ lowers blood glucose levels have not previously been investigated. Methods Wistar rats [250–300 g body ...
The use of directed evolution to create a stable and immunogenic recombinant BCG expressing a modified HIV-1 Gag antigen.

Chapman, Rosamund; Bourn, William R; Shephard, Enid; Stutz, Helen; Douglass, Nicola; Mgwebi, Thandi; Meyers, Ann; Chin'ombe, Nyasha; Williamson, Anna-Lise (2014-07-25)

Numerous features make Mycobacterium bovis BCG an attractive vaccine vector for HIV. It has a good safety profile, it elicits long-lasting cellular immune responses and in addition manufacturing costs are affordable. Despite ...