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Publication: Influenza or meningococcal immunization during pregnancy and mortality in women and infants
Clark, D.R. Omer, S.B. Tapia, M.D. Nunes, M.C. Cutland, C.L. Tielsch, J.M. Wairagkar, N. Madhi, S.A. BMGF Supported Maternal Influenza Immunization Trials Investigators Group
Clark, D.R.
Omer, S.B.
Tapia, M.D.
Nunes, M.C.
Cutland, C.L.
Tielsch, J.M.
Wairagkar, N.
Madhi, S.A.
BMGF Supported Maternal Influenza Immunization Trials Investigators Group
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Abstract
This analysis includes pooled data from 2 placebo-controlled maternal influenza immunization trials, with a separate analysis on a meningococcal conjugate vaccine-controlled maternal influenza immunization trial. Maternal influenza immunization was not associated with infant or maternal all-cause mortality in placebo-controlled trials. In the meningococcal conjugate vaccine-controlled trial, there were fewer deaths during low or any influenza circulation weeks among infants whose mothers received meningococcal conjugate vaccine. ClinicalTrials.gov identifiers: NCT01430689, NCT01034254 and NCT02465190.
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Date
2020-07
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Publisher
Wolters Kluwer Health
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Research Projects
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Keywords
Maternal immunization,Meningococcal,Influenza,Vaccine,Randomized controlled trial,SDG-03 Good health and well-being
Citation
Clark DR, Omer SB, Tapia MD, Nunes MC, Cutland CL, Tielsch JM, Wairagkar N, Madhi SA; for BMGF Supported Maternal Influenza Immunization Trials Investigators Group. Influenza or Meningococcal Immunization During Pregnancy and Mortality in Women and Infants: A Pooled Analysis of Randomized Controlled Trials. Pediatr Infect Dis J. 2020 Jul;39(7):641-644. doi: 10.1097/INF.0000000000002629.