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Listeria monocytogenes virulence, antimicrobial resistance and environmental persistence: A review

Matereke, L.T.
Okoh, A.I.
Abstract
Listeria monocytogenes is a ubiquitous opportunistic pathogen responsible for the well-known listeriosis disease. This bacterium has become a common contaminant of food, threatening the food processing industry. Once consumed, the pathogen is capable of traversing epithelial barriers, cellular invasion, and intracellular replication through the modulation of virulence factors such as internalins and haemolysins. Mobile genetic elements (plasmids and transposons) and other sophisticated mechanisms are thought to contribute to the increasing antimicrobial resistance of L. monocytogenes. The environmental persistence of the pathogen is aided by its ability to withstand environmental stresses such as acidity, cold stress, osmotic stress, and oxidative stress. This review seeks to give an insight into L. monocytogenes biology, with emphasis on its virulence factors, antimicrobial resistance, and adaptations to environmental stresses.
Description
Date
2020-07
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI
Research Projects
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Keywords
Listeria monocytogenes , Antimicrobial resistance , Biofilm , Environmental stress , Virulence
Citation
Matereke LT, Okoh AI. Listeria monocytogenes Virulence, Antimicrobial Resistance and Environmental Persistence: A Review. Pathogens. 2020 Jun 30;9(7):528. doi: 10.3390/pathogens9070528.
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