Chest ultrasound for the diagnosis of paediatric pulmonary diseases: A systematic review and meta-analysis of diagnostic test accuracy
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Date
2019-03-01
Authors
Heuvelings, C.C
Bélard, S
Familusi, M.A
Spijker, R
Grobusch, M.P
Zar, H.J
Journal Title
Journal ISSN
Volume Title
Publisher
Oxford Academic
Abstract
Background: Chest ultrasound is an emerging imaging modality, for several paediatric pulmonary diseases.
Sources of data: MEDLINE and EMBASE (1946-47 to 10 March 2017) were searched to collect evidence on the diagnostic accuracy of chest ultrasound, compared to other imaging modalities, for the diagnosis of paediatric pulmonary diseases.
Areas of agreement: Eighteen pneumonia studies, comprising 2031 children, were included for meta-analysis; the summary estimate sensitivity was 95.0% (95%CI: 90.7-97.3%) and specificity was 96.1% (95%CI: 89.1-98.7%).
Areas of controversy: Other pulmonary diseases also yielded high sensitivity and specificity, but a meta-analysis could not be conducted due to a limited number of studies includable, and their heterogeneity.
Growing points: Chest ultrasound should be considered as a first-line imaging modality for children with suspected pneumonia.
Areas timely for developing research: Further research should focus on the diagnostic accuracy of chest ultrasound for the diagnosis of paediatric pulmonary diseases, other than pneumonia, comparing against a valid gold standard.
Description
Keywords
pneumonia
Citation
Heuvelings CC, Bélard S, Familusi MA, Spijker R, Grobusch MP, Zar HJ. Chest ultrasound for the diagnosis of paediatric pulmonary diseases: a systematic review and meta-analysis of diagnostic test accuracy. Br Med Bull. 2019 Mar 1;129(1):35-51. doi: 10.1093/bmb/ldy041.