Friday 18th August 2023 update: login access to this repository is currently paused pending an upgrade to a new DSpace version in September 2023. If you have a query about submitting to this repository please contact the library repository administrators via the 'Contact Us' link in at the bottom of this page. FAO repository administrators: please do not add new items to the repository in this time and contact Atmire if any query.
Alcoholic liver disease: a synopsis of the Charles Lieber's Memorial Symposia 2009-2012.
Abstract
This paper is based upon the 'Charles Lieber Satellite Symposia' organized by Manuela G. Neuman at each of the 2009-2012 Research Society on Alcoholism (RSA) Annual Meetings. The presentations represent a broad spectrum dealing with alcoholic liver disease (ALD). In addition, a literature search (2008-2013) in the discussed area was performed in order to obtain updated data. The presentations are focused on genetic polymorphisms of ethanol metabolizing enzymes and the role of cytochrome P4502E1 (CYP2E1) in ALD. In addition, alcohol-mediated hepatocarcinogenesis, immune response to alcohol and fibrogenesis in alcoholic hepatitis as well as its co-morbidities with chronic viral hepatitis infections in the presence or absence of human deficiency virus are discussed. Finally, emphasis was led on alcohol and drug interactions as well as liver transplantation for end-stage ALD.