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dc.contributor.authorSanz, M Gen
dc.contributor.authorViljoen, Aen
dc.contributor.authorSaulez, M Nen
dc.contributor.authorOlorunju, Sen
dc.contributor.authorAndrews, F Men
dc.date.accessioned2016-01-28T10:32:45Zen
dc.date.available2016-01-28T10:32:45Zen
dc.date.issued2014-08-09en
dc.identifier.citationEfficacy of a pectin-lecithin complex for treatment and prevention of gastric ulcers in horses. 2014, 175 (6):147 Vet. Rec.en
dc.identifier.issn2042-7670en
dc.identifier.pmid24821856en
dc.identifier.doi10.1136/vr.102359en
dc.identifier.urihttp://hdl.handle.net/11288/595080en
dc.description.abstractThe objective of this study was to evaluate the effect of a commercial feed supplement containing pectin-lecithin on squamous mucosa ulceration in horses exposed to an experimental ulceration model. Five mares were treated while five mares were controls for this crossover, blinded study. The mares were fed concentrates and hay and were stabled with a two-hour turn out per day for a period of four weeks. The pectin-lecithin complex was fed for the duration of the study on the treated group. At the end of a four-week period, all mares underwent a seven-day alternating feed deprivation (week 5). The study was repeated again after a four-week washout period. Gastroscopy was performed on days 1, 28 and 35 of the study and was digitally recorded. Independent evaluation of the recordings and scoring of the lesions using the Equine Gastric Ulcer Syndrome (EGUS), severity and number scores were performed by three experienced gastroscopists. The prevalence and severity of squamous ulcers significantly increased after intermittent feed deprivation (P<0.001). No significant effect of the treatment was observed (P>0.05). In this study, the addition of a commercially available pectin-lecithin complex to the feed of horses for five weeks did not prevent or minimise the risk for gastric ulceration of the squamous mucosa.en
dc.language.isoenen
dc.relation.urlhttp://veterinaryrecord.bmj.com/cgi/pmidlookup?view=long&pmid=24821856en
dc.rightsArchived with thanks to The Veterinary recorden
dc.subjectpectin-lecithin complexen
dc.subjectgastric ulcersen
dc.subjectpreventionen
dc.subjecthorsesen
dc.subjecttreatmenten
dc.subjectEquine Gastric Ulcer Syndromeen
dc.subject.meshAnimal Feeden
dc.subject.meshAnimalsen
dc.subject.meshAnti-Ulcer Agentsen
dc.subject.meshCross-Over Studiesen
dc.subject.meshDietary Supplementsen
dc.subject.meshFemaleen
dc.subject.meshGastric Mucosaen
dc.subject.meshHorse Diseasesen
dc.subject.meshHorsesen
dc.subject.meshPectinsen
dc.subject.meshPhosphatidylcholinesen
dc.subject.meshStomach Ulceren
dc.subject.meshTreatment Outcomeen
dc.titleEfficacy of a pectin-lecithin complex for treatment and prevention of gastric ulcers in horses.en
dc.typeArticleen
dc.identifier.journalThe Veterinary recorden
dc.research.unitBiostatistics Uniten
dc.date.epub2014-05-12en


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