Iron, folate and vitamin B12 status of an elderly South African population

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dc.contributor.authorCharlton, K.E.
dc.contributor.authorKruger, M.
dc.contributor.authorLabadarios, D.
dc.contributor.authorAronson, I.
dc.contributor.departmentNational Research Programme for Nutritional Intervention, Medical Research Council, South Africaen_US
dc.date.accessioned2020-03-11T06:54:21Z
dc.date.available2020-03-11T06:54:21Z
dc.date.epub1997
dc.date.issued1997
dc.description.abstractObjectives: To determine the prevalence of anaemia and the haemopoietic nutrient status of older mixed ancestry (coloured) South Africans. Design: A cross-sectional analytic study. Subjects: A random sample of 200 non-institutionalized subjects aged 65 y of age, resident in urban Cape Town, was drawn using a two-stage cluster design. Methods: Trained ®eldworkers interviewed subjects to obtain demographic and lifestyle data. Dietary intake was assessed using a validated food frequency questionnaire. Fasting blood samples were drawn for the determination of haematological parameters, serum vitamin B12, serum folate, RBC folate and a full blood count. Results: The prevalence of anaemia was 13.9. Eight of the 26 cases of anaemia (31) were associated with suboptimal haemopoietic nutrient status; 2(25) and 3(38) cases of these 8 anaemic subjects had suboptimal vitamin B12 and folate status, respectively. Iron de®ciency anaemia accounted for 5(63) of the subjects with nutrition-related anaemia. Ten men and two women (6.5 of subjects) had raised serum ferritin concentrations, half of whom had abnormal biochemical parameters indicative of alcohol abuse. Conclusions: Older coloured South Africans, particularly women, should be encouraged to eat diets with a high nutrient density and to consume adequate amounts of foods high in iron, folate and vitamin B12. Further investigation regarding the high prevalence of hyperferritinaemia found in the men in this population is indicated. Sponsorship: Financial assistance from the HSRC/UCT Centre for Gerontology, the South African Sugar Association, the Zerilda Steyn Memorial Trust and the Medical Research Council (DL) for this project is acknowledged. Descriptors: vitamin B12; ferritin; folate; anaemia; elderly; South Africansen_US
dc.description.sponsorshipFinancial assistance from the HSRC/UCT Centre for Gerontology, the South African Sugar Association, the Zerilda Steyn Memorial Trust and the Medical Research Council (DL) for this project is acknowledged.en_US
dc.identifier.citationCHARLTON KE, KRUGER M, LABADARIOS D, WOLMARANS P, ARONSON I. Iron, folate and vitamin B12 status of an elderly South African population. European journal of clinical nutrition [Internet].en_US
dc.identifier.issn0954-3007.
dc.identifier.journalclinical nutritionen_US
dc.identifier.urihttps://infospace.mrc.ac.za/handle/11288/595224
dc.language.isoenen_US
dc.publisherBasingstoke: Nature Publishingen_US
dc.relation.urlhttp://pascal-francis.inist.fr/vibad/index.php?action=search&terms=2736723en_US
dc.research.unitClosed Unitsen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subjectNutrition, obesity, metabolic disordersen_US
dc.subjectBiological and medical sciencesen_US
dc.subjectMedical sciencesen_US
dc.subjectHematologic and hematopoietic diseasesen_US
dc.subjectDiseases of red blood cellsen_US
dc.subjectAnemias. Hemoglobinopathiesen_US
dc.subjectHemopathyen_US
dc.subjectSideropeniaen_US
dc.subjectIron deficiency anemiaen_US
dc.subjectClinical biologyen_US
dc.subjectEpidemiologyen_US
dc.subjectNutritional statusen_US
dc.subjectRisk factoren_US
dc.subjectIron ionen_US
dc.subjectFerritinen_US
dc.subjectFolateen_US
dc.subjectHumanen_US
dc.subjectHydroxocobalaminen_US
dc.subjectPrevalenceen_US
dc.subjectElderlyen_US
dc.titleIron, folate and vitamin B12 status of an elderly South African populationen_US
dc.typeArticleen_US
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