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Alcoholic liver disease: a synopsis of the Charles Lieber's Memorial Symposia 2009-2012.

Neuman, Manuela G
Cohen, Lawrence
Zakhari, Samir
Nanau, Radu M
Mueller, Sebastian
Schneider, Michelle
Parry, Charles
Isip, Romina
Seitz, Helmut K
Abstract
This paper is based upon the 'Charles Lieber Satellite Symposia' organized by Manuela G. Neuman at each of the 2009-2012 Research Society on Alcoholism (RSA) Annual Meetings. The presentations represent a broad spectrum dealing with alcoholic liver disease (ALD). In addition, a literature search (2008-2013) in the discussed area was performed in order to obtain updated data. The presentations are focused on genetic polymorphisms of ethanol metabolizing enzymes and the role of cytochrome P4502E1 (CYP2E1) in ALD. In addition, alcohol-mediated hepatocarcinogenesis, immune response to alcohol and fibrogenesis in alcoholic hepatitis as well as its co-morbidities with chronic viral hepatitis infections in the presence or absence of human deficiency virus are discussed. Finally, emphasis was led on alcohol and drug interactions as well as liver transplantation for end-stage ALD.
Description
Date
2014-07
Journal Title
Journal ISSN
Volume Title
Publisher
Research Projects
Organizational Units
Journal Issue
Keywords
Alcoholic Liver Disease , Synopsis , Charles Lieber's Memorial Symposia , genetic polymorphisms , ethanol metabolizing enzymes , cytochrome P4502E1 , Drug interactions , Alcohol interactions
Citation
Alcoholic liver disease: a synopsis of the Charles Lieber's Memorial Symposia 2009-2012., 49 (4):373-80 Alcohol Alcohol.
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